[11C]Flumazenil PET in Temporal Lobe Epilepsy: Do We Need an Arterial Input Function or Kinetic Modeling?
نویسندگان
چکیده
منابع مشابه
Serotonergic PET in temporal lobe epilepsy: biomarking or etiologic mapping?
PET and selected ligands offer brain mapping for a panoply of neuronal receptors and other important brain molecules. Neurochemically specific PET studies have yielded numerous biomarkers of hippocampal and extrahippocampal dysfunction, which often have been used to study groups with temporal lobe epilepsy (TLE). Etiologies and the development of epilepsy are poorly understood in TLE, however. ...
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Commentary Mesial temporal lobe epilepsy with hippocampal sclerosis tends to be drug resistant but usually has excellent outcome with epilepsy surgery. Despite the excellent prognosis overall , a substantial proportion of patients are not seizure-free after surgery, and it is important to identify these patients before surgery, if possible. The few studies that have investigated outcome predict...
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Temporal lobe epilepsy (TLE) is typically associated with long-term memory dysfunction. The frontal lobes support high-level cognition comprising executive skills and working memory that is vital for daily life functioning. Deficits in these functions have been increasingly reported in TLE. Evidence from both the neuropsychological and neuroimaging literature suggests both executive function an...
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متن کاملOptimizing memory function in temporal lobe epilepsy
PURPOSE The study aimed to assess whether engagement in a memory training programme and performing internet brain training exercises improve memory function in people with temporal lobe epilepsy (TLE). METHODS Seventy-seven people with TLE, complaining of memory difficulties, completed the study. Participants ranged in age from 19 to 67 years and 40 had left TLE. Participants were randomised ...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2007
ISSN: 0271-678X,1559-7016
DOI: 10.1038/sj.jcbfm.9600515